基因的表达与调控（英文版）
作者： 马骏
出版时间：2006-04-28
出版社：高等教育出版社
- 高等教育出版社
- 9787040176759
- 1版
- 227418
- 46254488-3
- 精装
- 大大16开
- 2006-04-28
- 1000
- 592
- 理学
- 生态学
- R318.04；Q786
- 生物、医学类
- 研究生及以上
Jun Ma is an Associate Professor at the Division of Developmental Biology,Cincinnati Children’s Hospital Research Foundation and University of Cincinnati College of graduated from Peking University in 1982,majoring in did his graduate work with Mark Ptashne at the Department of Biochemistry and Molecular Biology in Harvard University,and was a Junior Fellow at the Harvard Society of Fellows between spent the summer of 1988 in the laboratory of Christiane Nüsslein-Volhard at the Max-Planck-Institute for Developmental Biology in Tübingen to collaborate with Wolfgang joined the faculty of the University of Cincinnati College of Medicine in 1992 and has remained there rrently he also has a collaborative base at the Institute of Biophysics of the Chinese Academy of Sciences in s earlier work on the yeast activator GAL4 helped pave the way to the development of the yeast two-hybrid s current research focuses on the mechanisms of transcript on control and development in Drosophila.
front matter
Section I The History
Chapter01 Transcription: The Never Ending Story
Section II The Machinery
Chapter02 The General Transcription Machinery and Preinitiation Complex Formation
Chapter03 The Dynamic Association of RNA Polymerase II with Initiation, Elongation, and RNA Processing Factors during the Transcription Cycle
Chapter04 General Cofactors：TFIID, Mediator and USA
Chapter05 Chromatin and Regulation of Gene Expression
Chapter06 HATs and HDACs
Chapter07 Structure and Function of Core Promoter Elements in RNA Polymerase II Transcription
Section III The Regulators
Chapter08 Transcriptional Activators and Activation Mechanisms
Chapter09 Transcriptional Repressors and Repression Mechanisms
Chapter10 STATs in Cytokine-mediated Transcriptional Regulation
Chapter11 Transcriptional Regulation by Smads
Chapter12 The Rb and E2F Families of Proteins
Chapter13 c-Jun：A Complex Tale of a Simple Transcription Factor
Chapter14 HIV Tat and the Control of Transcriptional Elongation
Chapter15 Post-translational Modifications of the p53 Transcription Factor
Chapter16 Actions of Nuclear Receptors
Chapter17 NFAT and MEF2, Two Families of Calcium-dependent Transcription Regulators
Chapter18 Hox Genes
Chapter19 Nuclear Factor-kappa B
Chapter20 The ATF Transcription Factors in Cellular Adaptive Responses
Section IV The Genome
Chapter21 Function and Mechanism of Chromatin Boundaries
Chapter22 Heterochromatin and X Inactivation
Chapter23 DNA Methylation Regulates Genomic Imprinting, X Inactivation, and Gene Expression during Mammalian Development
Chapter24 Comparative Genomics of Tissue Specific Gene Expression
Chapter25 Transcription and Genomic Integrity
Chapter26 Cell Death and Transcription
Section V Special Topics
Chapter27 Pre-mRNA Splicing in Eukaryotic Cells
Chapter28 Genome Organization：The Effects of Transcription-driven DNA Supercoiling on Gene Expression Regulation
Chapter29 The Biogenesis and Function of MicroRNAs
Chapter30 Transcription Factor Dynamics
Chapter31 Actin, Actin-Related Proteins and Actin-Binding Proteins in Transcriptional Control
Chapter32 Wnt Signaling and Transcriptional Regulation
Chapter33 Regulatory Mechanisms for Floral Organ Identity Specification in Arabidopsis thaliana
Chapter34 Transcription Control in Bacteria
Chapter35 Gene Therapy：Back to the Basics
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